Biochemistry

1699 

• Simon Bouldec introduces a method of extraction for analysis of plants. He applies this on comparative research on classes of ipecacuanha. As extraction means he uses water and wine spirit   

200 years ago
1799 

• Antoine Françis de Fourcroy and Louis Nicolas Vauquelin prepare pure urea as the end product of the conversion of proteins in the bodies of animals. They name this product "urée"   

150 years ago
1849   

• Ebenhezer N Horford discovers a method to evaporate milk
• Bleunard prepares alanine as the separation product of legamin from peas   

100 years ago
1899 

• Jacques Loeb achieves the chemical fertilization (with magnesium chloride) of eggs of the sea-urchin
• Albrecht Kossel formulates his protamine- theory
• Martin Jacoby concludes that in case of hard diabetes no glycolysis occurs
• Cl Fermi  uses some fission fungues to produce proteolytic enzymes. These enzymes transform proteins, as glue and fibrine, into soluble compounds. So they are able to compose protoplasm
• W Spitzer  succeeds in transforming hypoxantine and xantine into urea using organ extracts (eg. spleen and liver from calf and cow)   

50 years ago
1949 

• Louis Frederick Fieser and Mary Fieser publish the 3rd edition of "Natural Products related to Phenanthrene"
• Edward Calvin Kendall  et al. discover cortisone as a special medicine for rheumatic arthritis
• Wolfgang Langenbeck  researches the relations of organic catalysts and enzymes
• Richard Kuhn  researches some problems of the biochemical genetics
• Adolf Butenandt, W Weidel  and H Schlossberger  determine the genes V+ and en- as prerequisites of specific ferments, which promote eg. the formation of ommochromic pigments by catalysis or the metabolism of tryptophan
• Karl Johann Freudenberg  discovers the formation of lignin-like substances under physiological conditions
• Gustaf Ehrhardt  discovers a new class of analgesics related to diphenyImethane